Botox®
- Active
- onabotulinumtoxinA
- Approval
- Approved 2002
- Formulation
- With accessory proteins
Services
A short menu, done well.
Two kinds of appointment: neuromodulator injections with Botox, Xeomin, or Letybo for expression lines, and PDRN mesotherapy for skin texture. Both with Janyll Birmingham, RN.
Neuromodulators
Botox, Xeomin, and Letybo.
Xeomin®
- Active
- incobotulinumtoxinA
- Approval
- Approved 2010
- Formulation
- No accessory proteins
Letybo®
- Active
- letibotulinumtoxinA
- Approval
- Approved 2024
- Formulation
- Standard formulation
Smoothing for forehead lines, frown lines (the “11s”), and crow’s feet. All three relax the small muscles that pull skin into expression lines. You still look like yourself, just less tense. All injections by Janyll Birmingham, RN.
If you’re new to tox, start with lines in motion, lines at rest, a short primer on how lines form and what tox does about them.
To see where on the face it can help, visit Face Areas.
PDRN mesotherapy
Mesotherapy with PDRN.
PDRN
Polydeoxyribonucleotide
- What it is
- A skincare ingredient made from purified salmon DNA.
- How it goes in
- Mesotherapy: a series of tiny, shallow injections that place it just under the surface of the skin.
- Good to know
- It comes from salmon, so tell us about any fish allergy when you book.
Tox relaxes the small muscles that fold skin into expression lines. PDRN works on the skin, with the focus on texture and how your skin looks and feels.
Some people book one, some book both. Before anything starts, we’ll talk about what you’d like to change and whether PDRN is a good fit for your skin. You’ll leave with written aftercare, and the care page covers how to get ready.
How we work
A different kind of medspa visit.
Visits run like a doctor’s appointment. Janyll starts with a small dose and explains what she’s doing as she goes. You decide how much to do today and how much to leave for next time.
Group appointments
Ten or more, at your place.
Sometimes called a Botox party. Janyll comes to you for a private group appointment, booked ahead for ten people or more. The per-person rate is discounted, and the discount grows with the size of the group.
It runs the same way an in-clinic visit does, with the same conversation and conservative dosing, one person at a time.
Send your date, your location, and roughly how many people. We’ll get back to you with the group rate and what we need from you.
- Minimum
- Ten people, confirmed ahead of the date.
- Group rate
- A discounted per-person rate that scales with how many people attend.
- What we need
- One well-lit room with a sink nearby, and somewhere private for each person’s intake.
- Every guest
- Completes their own health intake and consent with Janyll, privately, the same as an in-clinic visit.
Please hold off on alcohol until after your injections. It thins the blood and makes bruising more likely.
Common questions
Things to know.
Answers to the questions we hear most often. Anything else, we’ll go over at your appointment.
What's the difference between Botox, Xeomin, and Letybo?
All three are FDA-approved neuromodulators that relax the small muscles producing expression lines. The visible effect is essentially the same. Botox includes accessory proteins and has the longest track record. Xeomin is a pure formulation without those accessory proteins. Letybo is the newest of the three. We'll talk through which one fits at your appointment.
Do tox injections hurt?
The injections are small. You may feel a quick pinch, sometimes nothing at all. The visit itself is short, usually under fifteen minutes once we've talked through the plan.
How long does tox last?
Most people see effects last around three to four months. After several rounds, some find the interval between appointments lengthens.
When will I see results from tox?
Softening usually begins five to seven days after the appointment. Most of the change has settled in by about two weeks.
Is there any downtime after tox?
No real downtime. You can return to your day. We ask you to avoid lying flat or vigorous exercise for the rest of the afternoon, and to skip facial massage for twenty-four hours.
Will I look frozen?
We dose conservatively, so you should still look like yourself, just less tense around the eyes and brow.
What is PDRN, and how is it different from tox?
PDRN stands for polydeoxyribonucleotide, a skincare ingredient made from purified salmon DNA. With mesotherapy, it is placed just under the surface of the skin through a series of tiny, shallow injections. Tox relaxes the muscles behind expression lines, while PDRN works on skin texture and how your skin looks. Because PDRN comes from salmon, tell us about any fish allergy when you book.
Do you do group appointments, sometimes called a Botox party?
Yes, for groups of ten or more. Janyll comes to your location for a private group appointment, and the per-person rate is discounted based on how many people attend. Every guest completes their own health intake and consent privately, the same as an in-clinic visit, and we ask that no one drink alcohol beforehand. Email info@thedose.clinic with your date, your location, and roughly how many people.
Ready when you are
Come in for an appointment.
Appointments are in San Rafael. We’ll go over your options and dosing with you before anything starts.